Archive for the ‘Science’ Category

The Aseem Malhotra lecture isn’t what you think it is

February 14 | Posted by mrossol | Critical Thinking, Science, Vaccine

Interesting. I did not read the lecture by Dr. Malhotra, but can sort of guess(?) It is helpful to consider other viewpoints, so I wanted to include it – since I probably don’t do enough of that. mrossol Source: The Aseem Malhotra lecture isn’t what you think it is | Science-Based Medicine For those audience members unfamiliar with Dr. Aseem Malhotra... Read more

The “evidence pyramid” should be dismantled, brick by ill-conceived brick

February 13 | Posted by mrossol | Critical Thinking, Math/Statistics, Prasad, Science

Source: The “evidence pyramid” should be dismantled, brick by ill-conceived brick I wrote last week about a systematic review of physical measures to block viral transmission. In the post I referenced the famous (or perhaps infamous) evidence pyramid. My goal was to show the idealized version of evidence—wherein a systematic review of randomized trials strengthens one’s confidence in any one trial’s... Read more

It was cruel to trick people that they can protect immunocompromised loved ones by masking & being precautious

February 8 | Posted by mrossol | Coronavirus, Health, Science

By Vinay Prasad, Feb 8, 2023 Source: It was cruel to trick people that they can protect immunocompromised loved ones by masking & being precautious

There are still some people taking precautions because they know someone who’s immunocompromised or live with someone who’s immunocompromised. We have set these people up for failure. Public health has lied to them. First,... Read more

Public health is not like medicine: It doesn’t have to generate evidence

February 7 | Posted by mrossol | Health, Ruling Class, Science, The Left, WHO

By Vinay Prasad, Feb. 7, 2023. Source: Public health is not like medicine: It doesn’t have to generate evidence

During the pandemic, the same person who says “this observational study of <insert cancer drug> can’t prove it works because of residual confounding” is happy to say, “this observational study of community masking proves it works.” Bizarre, right? If... Read more

Wide confidence intervals means an intervention could still work; Is that the standard we always use in medicine?

February 7 | Posted by mrossol | Critical Thinking, Science

Bt Vinay Prasad, February 6, 2023 Source: Wide confidence intervals means an intervention could still work; Is that the standard we always use in medicine?

I took the liberty of plotting the largest randomized trials of masking from the Cochrane review, and, first off, as you can see, all the confidence intervals are wide, and compatible with important... Read more

Let’s Do the Cochrane Review of Physical Measures to Reduce the Spread of Viruses

February 7 | Posted by mrossol | Critical Thinking, FDA, Science

By John Mandrola, February 6, 2023 Source: Let’s Do the Cochrane Review of Physical Measures to Reduce the Spread of Viruses Professor Tom Jefferson of Oxford led a large group of authors for this fifth update of the evidence review of physical measures to interrupt the spread of respiratory viruses. Their last review was in 2020, which did not include SARS-CoV-2 infection. Background... Read more

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